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“The analogy is pretty good. In our search box, you can upload a list of genes, and with one click, the analysis is computed,” said Justin Lamb, the lead author of the Science paper and a senior scientist in the Broad Institute?...

Author: By Anupriya Singhal, CRIMSON STAFF WRITER | Title: Researchers Invent “Google” for Disease | 10/3/2006 | See Source »

Those molecular switches lie in the noncoding regions of the genome--once known dismissively as junk DNA but lately rechristened the dark matter of the genome. Much of the genome's dark matter is, in fact, junk--the residue of evolutionary events long forgotten and no longer relevant. But a...

Author: /time Magazine | Title: What Makes us Different? | 10/1/2006 | See Source »

What causes changes in both the dark matter and the genes themselves as one species evolves into another is random mutation, in which individual base pairs--the "letters" of the genetic alphabet--are flipped around like a typographical error. These changes stem from errors that occur during sexual reproduction, as...

Author: /time Magazine | Title: What Makes us Different? | 10/1/2006 | See Source »

The Neanderthals weren't nearly as primitive as many assume, observes Eddy Rubin, director of the Department of Energy's Joint Genome Institute in Walnut Creek, Calif. "They had fire, burial ceremonies, the rudiments of what we would call art. They were advanced--but nothing like what humans have done...

Author: /time Magazine | Title: What Makes us Different? | 10/1/2006 | See Source »

Some of the differences could have enormous practical consequences. Since his discovery that human cells lack one specific form of sialic acid, which was accomplished even before the human genome was decoded, Varki and his collaborators have determined that 10 of the 60 or so genes that govern sialic-acid...

Author: /time Magazine | Title: What Makes us Different? | 10/1/2006 | See Source »

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