Word: geneticists
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Leder is also very short on administrative experience. Once rumored to be the frontrunner, enthusiasm on behalf of the 56-year-old geneticist now appears to have flagged...
...correlations are not the same as proving cause and effect. Many researchers argue that there are probably several life-style factors rather than a single culprit. "The high rates are not due to one bad habit, but to our whole way of life," says Mary-Claire King, a cancer geneticist at the University of California, Berkeley...
Recent months have brought a series of discoveries about the genetic mutations involved in breast cancer. "Information is accumulating at an astounding rate," says University of Utah geneticist Mark Skolnick. Changes in at least two types of genes play a role: those that direct cells to grow and divide; and those that issue commands to halt growth. Much of the research has focused on a growth-enhancing gene on chromosome 17, often referred to as the HER-2/neu oncogene. An estimated 30% of breast-cancer patients have somehow acquired abnormal quantities of this gene -- as many...
...other patients, says UCLA oncologist Dr. $ Dennis Slamon. Such patients, he says, should "absolutely" get further treatment. But one genetic abnormality is not enough to transform healthy, law-abiding breast cells into anarchic tumors. "The genes responsible for this disease are like pieces of a patchwork quilt," says geneticist Mary- Claire King of the University of California, Berkeley. The patchwork pattern may vary from one woman to the next, but each case probably involves five or six separate mutations occurring over a period of years...
...much a philosopher as a geneticist, and he has thought a great deal about his first cousin once removed, Dwight David Eisenhower. Jackson believes the bedrock of Ike's achievements and his growing stature in history came from the white frame house in Abilene and the harmony the town required and imposed for a rewarding life. Many strata of worldly experience were laid down over Ike's character during his 50 years of public service. But the final high silhouette of his life followed the outlines shaped in the streets of Abilene...