Word: giacomini
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...everyone could understand it. It is not easy and simple to face that change in our life, but we must accept it without falling into depression. It is true that with therapy and medical help things can really change and we can look at life through different eyes. Adriana Giacomini Donato Colloredo di Prato, Italy
...known to play a role in drug absorption and elimination. The first step is to look at the genes for those transporters in DNA samples from 250 ethnically diverse people and see how they vary from one individual to the next. "Identifying the variants is rather easy," says Kathleen Giacomini, the project's principal investigator and UCSF's chairwoman of biopharmaceutical sciences. "The really hard part is in looking at whether the variants have significance for drug response...
...response to a particular body chemical--serotonin, for example, a neurotransmitter implicated in clinical depression--varies. Then they bathe the cells in Prozac, for instance, which works by modifying serotonin levels in the brain, and see how that response changes. "If there's a difference," says Giacomini, "I'll know that maybe your transporter interacts with the drugs a little differently from mine...
...face of such an uprising, Progressivite Montanari hustled abroad, left Party-lining Foreign Minister Gino Giacomini to cope with mutinous parents, including many loyal Communists. Said Giacomini soothingly: "We don't want to persecute anyone, certainly not dear Mother Veronica." At week's end, the closing order remained in effect, but parents were still entrusting their daughters to Mother Veronica's medieval-minded ways. Explained the wife of Communist Party Secretary General Gildo Gasperoni: "Her school is better than the others...
Said Gino Giacomini, the republic's Foreign Secretary (and a Socialist): "They offend the dignity and the autonomy of our republic. Dear friend, it is a very bitter pill." The republic had to swallow it. At week's end, San Marino restored its law against gambling, shut up its casino. Demo-Christian Leader Teodoro Lonfernini found a little to cheer him: "We may not have much money, but at least we have had a good housecleaning...
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