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...statin and fibrate study, about 5,500 patients with diabetes and at least one other health problem were given cholesterol-lowering statins; half were also given a triglyceride-lowering fibrate. There was no difference in heart-attack and stroke rates between the groups. (See the top 10 medical breakthroughs...

Author: /time Magazine | Title: Why Drugs Don't Help Diabetes Patients' Hearts | 3/16/2010 | See Source »

...researchers had hoped that treated patients would lower their risk of heart events because they were given both statin drugs, which curb the liver's production of cholesterol, and a fibrate, which mops up harmful triglycerides in the blood and boosts levels of "good" cholesterol. But all of the volunteers either already suffered from heart disease, or had two or more major risk factors for heart problems - including cigarette smoking, family history and high cholesterol - in addition to diabetes. That may have pushed their diabetes too far along to allow them to see any benefit from the drugs. "This...

Author: /time Magazine | Title: Why Drugs Don't Help Diabetes Patients' Hearts | 3/16/2010 | See Source »

...Given that such aggressive drug treatment does not seem to afford significant benefits to diabetics on the whole, Saudek and his colleagues anticipate that going forward physicians and patients will increasingly reintroduce the importance of lifestyle changes, such as improving diet and getting more physically active, for slowing the progression of diabetes and reducing the risk of heart disease. These are therapies that are, after all, proven to work. "These discussions obviously should be going on the whole time, but these studies are one more reminder that medication therapy has its downsides," says Einhorn...

Author: /time Magazine | Title: Why Drugs Don't Help Diabetes Patients' Hearts | 3/16/2010 | See Source »

...seem to be doing much damage to Rubio's surprising, and widening, lead in the polls. Before the relatively unknown 38-year-old Rubio became the darling of angry conservatives last summer, the race for the Florida Senate seat - one of the most important up for grabs in 2010, given the Sunshine State's bellwether status - looked like a walk on the beach for Crist, who led some polls by almost 30 points. Since then, Crist's bipartisan style, including his embrace of President Obama's $787 billion economic-stimulus plan and his performance as recession-racked Florida's chief...

Author: /time Magazine | Title: In Florida, Can Crist Turn the Tide Against Rubio? | 3/15/2010 | See Source »

...allies seek the final cache of votes required to clear the next hurdle in the House, they have one hand tied behind them. Business-as-usual eleventh-hour incentives are off limits after the pointed backlash against a spate of clumsy sweetheart deals like the so-called Cornhusker Kickback given to Nebraska Senator Ben Nelson. That's why the reality for the Democratic Party - that they must all hang together on the health care vote or they will surely all be hung separately in the midterm elections - is at the center of the case the President is now making, both...

Author: /time Magazine | Title: What a Health Care Loss Would Mean for Obama | 3/15/2010 | See Source »

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