Word: glioblastoma
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...working with a substance that targets a receptor for another growth factor called PDGF (platelet-derived growth factor). This receptor studs the surfaces of cells in certain ovarian, prostate, lung and brain tumors. Malkin has been testing the drug, SU101, on patients with an extraordinarily deadly brain tumor called glioblastoma. Median survival for a patient found to have this cancer is 14 months...
...drug, manufactured by Sugen, appears to slow or arrest tumor growth in about a third of glioblastoma patients, but it's too soon to say how long the benefits will last. Side effects appear to be mild. "We have one patient who's been on it for two years and three months," says Malkin. "His tumor is still there, but it's stable. He's alive; he's at work. For someone with recurrent glioblastoma, that's remarkable...
...utility-company employee, Coe began to have seizures, with temporary impairment of speech, about two years ago. An operation in March 1965 was successful in that it resulted in the removal of most of a brain tumor. But it also disclosed that the trouble was a malignant glioblastoma. "Though my husband got along well then with medicine," says Mrs. Coe, "the doctor told me the growth was extensive, and he probably wouldn't live more than about 18 months...