Word: glioblastomas
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...tumor and begin to grow uncontrollably, they need to induce the formation of new blood vessels to bring them oxygen and nutrients—a process known as angiogenesis. A team of researchers at Massachusetts General Hospital has discovered that the main effects of an angiogenesis inhibitor in treating glioblastoma, a severe kind of brain tumor, stem from the reduction of brain swelling, rather than any effect on tumor growth. In these tumors, blood vessels can be leaky, which causes swelling in the brain known as edema. This, in turn, can cause drowsiness, loss of consciousness, and brain damage...
Imagine being diagnosed with a glioblastoma, the most common—and deadly—type of brain tumor. Now imagine that with a single injection, your brain cells could be engineered to secrete a protein that would eliminate the tumor...
...committee chaired by Phillip Sharp, a Nobel Prize--winning cancer researcher at MIT. The selected projects will then be monitored by the American Association for Cancer Research. "What I hope to do is identify areas where we could accelerate progress, particularly in areas where there's need--ovarian, pancreatic, glioblastoma," says Sharp...
...Amsterdam, and another, slated to begin in mid-October, is currently awaiting final approval by the ethics committee at the University Hospital in Tübingen, Germany. There, in the renowned old research institution in the German southwest, neuro-oncologist Dr. Johannes Rieger wants to enroll patients with glioblastoma and astrocytoma, aggressive brain cancers for which there are hardly any sustainable therapies. Cell culture and animal experiments suggest that these tumors should respond particularly well to low-carb, high-fat diets. And, usually, these patients are physically sound, since the cancer affects only the brain. "We hope, and we have...
...surgeon removes as much of the tumor as possible, small drug wafers are inserted at the tumor sites. Over time the wafers slowly release a chemical that prevents the recurrence of new tumors. The technique seems to work. A 1997 clinical trial showed that after two years, 31% of glioblastoma patients with implanted wafers were still alive, compared with only 6% in the control group...