Word: globulin
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Dates: during 1970-1979
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...Ayres starred as the young German soldier named Paul Baumer; today he is played by Richard Thomas, the onetime John Boy of The Waltons. Ernest Borgnine portrays Stanislaus Katczinsky, the Polish veteran who instructs the raw army recruits. Borgnine and the rest of the cast had to take gamma globulin shots to protect themselves against a countrywide epidemic of a hepatic disease. Location shooting is hell...
...test his theory, Riggio has been injecting gamma globulin from human placentas, which are usually discarded after delivery, into patients at the hospital's Rogosin Kidney Center. He hopes that the placental extract will transfer blocking antibodies into them. That then might encourage acceptance of new organs. A positive sign: when Riggio examined long-term transplant survivors at the center, he found that their acceptance of kidney grafts somehow appeared to have been enhanced by a biochemical mechanism similar to that postulated in pregnant women...
Once, the only treatment for Rh disease was to replace virtually the entire fetal blood supply with massive transfusions before or shortly after birth. Now prevention is possible in the form of a blood extract called Rh immune globulin. Developed independently by research teams in England and the U.S. nearly a decade ago, the globulin acts as a vaccine to curtail the Rh-negative woman's production of antibodies and greatly reduces the risks to future Rh-positive children...
...John Gorman, one of the American researchers, warns that the vaccine works only if the woman is not already immune to Rh factor. He recommends that the globulin be given automatically to every woman within 72 hours of her first delivery, abortion or miscarriage if tests show that she is Rh-negative and the baby is Rh-positive. Says he: "You've got to get in during the time that the window is open...
...vaccine. But in Italy, the vaccine is now given to only 30%, while in Venezuela, only 5% of Rh-negative mothers get the shots. Even in the U.S., where 85% are now protected, the gap is still significant. Only half of the women now undergoing abortions receive Rh immune globulin after their operations...