Word: globulin
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...after five years of testing, a new blood extract called RhoGAM has arrived on the market. It enables doctors to protect each subsequent child by merely inoculating the mother. RhoGAM consists of a gamma-globulin fraction rich in Rh antibodies. Injected into the Rh-negative mother's bloodstream no later than three days after a miscarriage or the birth of her first Rh-positive child, it curtails her immune mechanism's production of antibodies and lessens the danger to future Rh-positive children. The inoculation must be repeated after each miscarriage or birth, but the tests show that...
...Jacques Gottlieb, of Detroit's Lafayette Clinic, told a tale of three laboratories: Lafayette, the Massachusetts' Worcester Foundation for Experimental Biology, and the Soviet Academy of Sciences' Institute of Psychiatry. Independently, each had discovered increased amounts of a component of the alpha-2-globulin fraction in the blood of schizophrenia victims. Alpha-2-globulin is a normal part of blood plasma, containing many proteins. In the blood of 60% of the schizophrenics studied by Gottlieb, the fraction was present at far-above-normal levels. The excessive alpha-2-globulin, Gottlieb theorizes, may perforate brain-cell walls...
...disease takes the form of a deficiency in antihemophilic globulin--Factor VIII. In normal humans the Factor VIII level in the blood stream ranges from 50 to 200 per cent. Hemophiliacs generally have a Factor VIII level of less than 25 per cent...
...patients-who had died of some cause other than a liver disease. Before implantation, the donated liver was matched for tissue and blood cells. To further assure a reasonable chance of success, Starzl and his colleagues gave their young patients injections of azathioprine (Imuran), prednisone and antilymphocyte globulin-all of which help to suppress immune reactions. The antilymphocyte globulin, newly developed from the blood of horses that have reacted to human tissue, is already helping to improve the chances (now estimated at 65%) of successful kidney transplantation as well...
...glands, spleens and lymph nodes are removed from human cadavers, and the extract is injected into horses. The horses' rejection mechanism goes to work and makes particles active against the human lymphocytes. The horses are later bled, antilymphocyte serum is extracted, and may be further refined to a globulin fraction. At the University of Colorado, a team headed by Dr. Thomas Starzl has performed 19 successful transplants since last June; given antilymphocyte globulin, the patients have got along well on sharply reduced doses of azathioprine and prednisone...