Word: glowacki
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...conventional transplants, the grafted material serves as scaffolding for bone cells migrating from adjacent tissue. But, the researchers say, something else apparently happens with demineralized bone: it induces the host tissue to form completely new bone. "This material changes the cells it comes in contact with," Biochemist Julie Glowacki explains. Fibroblasts, the cells that produce the connective tissue in the body, become osteoblasts, which are bone-producing cells. Though no one knows why the conversion occurs, scientists speculate that the demineralized material delivers an electrical signal to surrounding cells...
...last week announced that they had perfected a method for inducing bone growth by using crushed cadaver bones instead of bones removed from patients' bodies. Osteoinduction--the name of the new process--should be 100-per-cent effective, compared to grafting's success rate of 65 per cent, Julie Glowacki, head of the research team that developed the new process and an associate in surgery at the Med School, said last week. Using the new process, doctors implant demineralized bone matter into the site where bone growth is desired. The implant then causes existing non-skeletal tissue cells to change...