Word: goodness
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...amazed at how many people don't use shopping lists at all, or if they do, they're inadequate. These are the same people who said they don't have time to use coupons, and I say, the amount of time you're going to save by making a good list will more than make up for the time...
...Though ESPN is still Disney's cash cow, the 3-D channel will carry significant risks. In addition to added production costs, there's a more crucial issue facing ESPN: whether people are ready to fork over big bucks to upgrade their television sets, just for a few good games. Yes, consumers can expect more 3-D content to be rolled out over the next few months. But will there be enough to justify what could be a $4,000 purchase, in a sticky economy, by the time ESPN 3-D launches? Plus, will the consumers who have already dropped...
...game. "If you look back at the HD experience, we had a similar amount of content that we're offering now in 3-D," he says. "But viewers saw the future, bought into the vision and invested, and now the deployment of HD sets is significant. We feel very good about where we are." And come June, ESPN will show sports fans where they are going. Look out for the flying soccer balls...
Epigenetics brings both good news and bad. Bad news first: there's evidence that lifestyle choices like smoking and eating too much can change the epigenetic marks atop your DNA in ways that cause the genes for obesity to express themselves too strongly and the genes for longevity to express themselves too weakly. We all know that you can truncate your own life if you smoke or overeat, but it's becoming clear that those same bad behaviors can also predispose your kids - before they are even conceived - to disease and early death...
...good news: scientists are learning to manipulate epigenetic marks in the lab, which means they are developing drugs that treat illness simply by silencing bad genes and jump-starting good ones. In 2004 the Food and Drug Administration (FDA) approved an epigenetic drug for the first time. Azacitidine is used to treat patients with myelodysplastic syndromes (usually abbreviated, a bit oddly, to MDS), a group of rare and deadly blood malignancies. The drug uses epigenetic marks to dial down genes in blood precursor cells that have become overexpressed. According to Celgene Corp. - the Summit, N.J., company that makes azacitidine - people...