Word: gorman
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...American Medical Association unpeeled a surprising new finding: Contrary to popular assumption, eating one egg a day does not significantly increase the risk of heart attack or stroke. The study essentially debunked the common train of thought that had given eggs a bum rap, explains TIME medical columnist Christine Gorman. ?Scientists have known that eating eggs increases blood cholesterol, and they have also known that people with increased blood cholesterol face a greater risk of heart disease,? she says. But they jumped too quickly to conclude that eating eggs therefore increases heart disease...
Reports that the mega-successful new painkiller Celebrex has been linked to 10 deaths and 11 cases of gastrointestinal hemorrhage during its first three months should not lead to any hasty conclusions, warns TIME medical columnist Christine Gorman. So far, it is unclear how the new data on deaths and severe reactions, first reported in the Wall Street Journal on Tuesday, is related to the drug, or whether other factors may be involved. Celebrex, the first of a new class of Cox-2 inhibitors to hit the U.S. market, has taken off nearly as explosively as Viagra did, with some...
...disturbing data is drawn from the FDA's adverse events database, which routinely collects information about patient experiences with drugs from doctors, pharmacists and the drug companies themselves. As such, the reports are merely "observations that certain patients took the drug and then something happened," Gorman explains. But until the incidents are investigated, it is impossible to say whether a given reaction was caused by the drug or by other factors. The complications may have been precipitated, for example, by a patient's other medicines, illnesses or conditions, and may have nothing to do with the drug. In the case...
...drug reporting system is a "supersensitive one, not necessarily an accurate one," says Gorman, and that is appropriate. The goal of collecting this data is to raise any red flags early to focus further investigation and research in case patients are experiencing problems with a drug. However, "what is interesting in this case," Gorman notes, "is that what is being reported is exactly what is not supposed to happen with this drug." Since Celebrex was expected to cause fewer stomach problems than some other painkillers, the suggestion that it may be causing severe gastrointestinal reactions is surprising...
...suggests that Alzheimer?s may eventually be beaten. Along with academic researchers, many drug companies are hot on the trail of the disease. ?And pharmaceutical companies don?t spend the time and money to study things unless they think they have a good chance of developing a drug,? says Gorman. Thursday?s report gives encouragement that further study may eventually yield a payoff. But for now many questions still remain to be answered, not the least of which is this: If presenilin is indeed shown to be involved in causing Alzheimer?s disease, is it the only, the main...