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Stanford's 1959 Nobel Laureate Arthur Kornberg and Biochemist Mehran Goulian began their historic synthesis with four off-the-shelf inert chemical compounds called nucleotides-the basic building block of the DNA molecule, which controls the hereditary characteristics of every living thing. To these they added one enzyme, DNA polymerase, that is known to promote the assembly of nucleotides into the typical helix-shaped strand that characterizes the DNA molecule, and another enzyme that closes the strand into a ring...

Author: /time Magazine | Title: Molecular Biology: Closer to Synthetic Life | 12/22/1967 | See Source »

...Nobel Prize in Medicine for producing the first synthetic DNA molecule. Unlike the 1967 model, however, it was biologically inactive. He has received other awards for his work with enzymes and hopes next to learn how an enzyme like DNA polymerase actually organizes nucleotides into DNA molecules. Bio chemist Goulian worked under Korn berg as a postdoctoral fellow, and is now on the faculty of the University of Chicago Medical School. Sinsheimer is an authority on viruses, has specialized in the study...

Author: /time Magazine | Title: Molecular Biology: Closer to Synthetic Life | 12/22/1967 | See Source »

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