Word: grabowski
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...Similarly, on Oct. 19, PhRMA put out a statement calling for a "fair period of data protection" of 12 years at a "bare minimum." To defend its position, the group cited Duke University economist Henry Grabowski, whose work it has funded, and two patient groups. One, called RetireSafe, receives regular infusions of "general operating support" from Pfizer and operates out of a small Washington law-firm office. It has been blitzing Capitol Hill with letters arguing that guaranteeing biologics makers fewer than 12 years of exclusivity in the use of their data could cost lives. The other group, the Alliance...
...other side has resources of its own. The biggest generic-drug company, Teva Pharmaceuticals, has spent more than $2 million on lobbying and also sponsored academic work on the issue, aiming to disprove Duke's Grabowski. Generic-drug manufacturers are allied with such powerful organizations as AARP, labor unions, insurance companies, health-maintenance organizations and health-reform advocacy groups. There will be fights on the House and Senate floors and ultimately a House-Senate conference committee, on which Waxman will be a key voice. "The war is not over," he has warned. "If you know me at all, you know...
...however, studies of dexamphetamine and similar drugs have not revealed major safety problems. Although a few patients have had psychotic episodes from using "on top," those particular patients turned out to have previously suffered psychosis. "There's pretty consistent evidence that the side effects are generally nominal," says John Grabowski, a professor of psychiatry at the University of Minnesota who has championed the study of stimulant maintenance treatment...
...newer stimulant drug, modafinil, does not carry the same addiction risk as amphetamines, making it a promising alternative as a maintenance drug. But it's also less effective in treating the most severe addictions, according to Grabowski. "In our research, we were able to separate out [the more and less severely addicted patients], and the more severe people were more responsive to the more potent stimulants," says Grabowski, who has conducted two randomized controlled trials involving nearly 200 patients, which found that dexamphetamine treatment reduced cocaine use better than a placebo...
...maintenance is a panacea or that it will work for every cocaine or meth addict. But there is no medical treatment that works 100% of the time. "I think we have found something of potential benefit, and it should be met with interest and further research, rather than disdain," Grabowski says...