Word: grants
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What's more, the lean times come in a period when the cost of research has outpaced inflation, so there's a double hit. The NIH has a "pay line" of roughly 14%, meaning it hands out only that percentage of the total money requested. Just 1 in 10 grant proposals it considers "meritorious"--that is, worthy of funding--gets a payout...
There are opportunity costs to this system. Collaboration suffers as scientists guard their work to keep the money coming. Because the funding process favors experienced grant writers, young investigators can lose out. Such friction and lack of funds, some argue, are causing a brain drain to Singapore and other regions that are actively seeking to develop their biotech industries. "The incentives are totally misaligned. The repetitive nature of funding the same universities and the same people--all of these things add up to the stagnant position that we're in," says Doug Ulman, president of the LAF and chairman...
...MMRF benefited from the aggressive work of founder Kathy Giusti, a multiple-myeloma survivor and former pharmaceutical executive. When she and her group first raised enough money to start funding research, she faced a feeding frenzy of research applicants. "They will do what they have to do to get grant money. They're desperate," she says...
...MMRF made sure it got the most from its grant dollars by adopting an enforced-collaboration model in 2004, linking work at four cancer centers into a consortium managed by PricewaterhouseCoopers and providing them all with patients, tissue samples and a set of targets and goals. "The odds of a cure coming from one center are nil," Giusti says. "You need a mutual fund to fight cancer." From not having a single drug in the pipeline, the MMRF now has 30, half of them in clinical trials. The average lifespan of a multiple-myeloma patient has been extended by three...
...institute has also been very successful at reeling in research grants, as it has won over 40 percent of the grants it has applied for, according to Broad. Reflecting this success, Broad researchers announced just this week that they had received a six-year $86 million grant from the National Institutes of Health to support research to identify and develop molecular tools to signal pathways and cellular processes crucial to human health and disease...