Word: griseofulvin
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Dates: during 1960-1969
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...barber's itch, athlete's foot, and jockstrap itch. Last week 300 specialists in fungus infections, convened in Manhattan under auspices of the New York Academy of Sciences, agreed that 1959 had marked a turning point in the history of man and his itches: a new antibiotic, griseofulvin (extracted from a Penicillium species closely related to the source of penicillin), is the best remedy so far discovered for fungus infections that obligingly concentrate on the body's outer surfaces...
...While griseofulvin, taken by mouth, has proved remarkably successful against external fungal infections, most researchers have reported it useless against internal (systemic) infections. Mexico's Dr. Antonio González-Ochoa worried about this, tried griseofulvin against several deep-seated fungal infections. In all but one it failed. The exception was sporotrichosis, in which Sporotrichum schenckii attacks the lymph nodes and often causes hidden ulcers. In his first two patients treated with griseofulvin, he found the antibiotic as effective as the conventional potassium iodide treatment. Dr. González-Ochoa's conclusion: the idea that griseofulvin is useful...
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