Word: groopman
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...think [that plan] would have any effect because the Institute is a group of free standing, non-profit individuals," says Dr. Jerome Groopman, who co-directs the Center for Clinical Care with Hirsch...
Using bioengineering techniques, medical researchers have begun to mass- produce these substances and use them, sometimes in combined "cocktails," to boost the immune system against specific diseases. In clinical trials at Boston's New England Deaconess Hospital, Dr. Jerome Groopman has found that granulocyte-macrophage colony-stimulating factor reverses bone-marrow failure and boosts white-cell counts in AIDS patients. Gamma interferon seems to remedy the defective functioning of monocytes and macrophages in a wide variety of diseases. Alpha interferon has been particularly effective against two types of leukemia and non-Hodgkin's lymphoma, a cancer of the lymph system...
Victims of AIDS must not only combat the virus that causes the disease but must also fend off potentially fatal infections that overrun their weakened immune systems. A team of researchers in Boston and Los Angeles, led by Hematologist Jerome Groopman of New England Deaconess Hospital, reported in the New England Journal of Medicine last week that a genetically engineered version of a naturally occurring hormone partially restored depressed immune systems in 16 AIDS patients...
Known as granulocyte-macrophage colony-stimulating factor, the drug boosted the victims' count of white blood cells, the body's primary defense against infection, after just ten days of treatment. The additional cells could help AIDS patients fight off bacteria, viruses and other life-threatening microbes. Groopman believes GM-CSF could one day be used to treat a variety of diseases. "This is the first time that anyone has been able to regulate the white- blood-cell count in man," he says. "There are implications for cancer patients and people with bone-marrow disorders...
...life for more than just a few months or if it has any serious long-term side effects. And they were confident that AZT is not the ultimate weapon against AIDS, that other, more effective drugs will come along. "This is not the end of the story," says Jerome Groopman. "It's exciting to have a drug that appears to benefit patients with AIDS, but there's a lot more work that has to be done...