Word: guan
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According to Guan, part of the theory behind her research, discovered by members of the lab team she works with, is that proteins that are not water-soluble tend to clump together, thereby diminishing the ability of each protein to function. When the residues of these GFP proteins are positively charged, however, they have the ability to penetrate cell walls. Additionally, these super-charged proteins demonstrated the ability to carry nucleic, and even genomic, material into cells if the material was negatively charged...
...Guan didn’t seek out the Liu lab; rather, her interest in directed evolution, a major part of her life since her junior year of high school, allowed it to effectively find...
...Guan, a resident of Eliot House from Florida, was born in China and has lived in four countries to date because of her mother’s occupation. The summer before starting her job at the Liu laboratory, Guan attended the International Genetically Engineered Machine competition (iGEM), in which student teams design and create biological systems in living cells. David Thompson, the graduate student who is currently running the project Guan is working on, happened to be the teaching fellow working with Guan’s group at iGEM...
...After the competition], he contacted me directly to join the lab,” Guan said...
...These supercharged fluorescent proteins may hold promise,” Guan said, “as a very nontoxic, very efficient way to deliver therapeutic agents into cells...