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First, the current treatment regimen requires patients take a cocktail of four drugs, all nearly half a century old, for at least six months. The logistical and financial hurdles associated with paying for and completing treatment, however, virtually guarantee noncompliance and relapse. Second, in a cascade effect, noncompliance selects for drug-resistant strains of the mutated pathogen, precipitating the rise of multi-drug resistant and extremely drug-resistant tuberculosis. Treatment for drug-resistant TB with second-line drugs is astronomically more expensive, more time-intensive, and associated with more toxic side effects. Third, the rise of TB and human immunodeficiency...
...therapeutic regimens represent, however, only half the solution. Without commensurate scale-up of community-based treatment programs—the “social” dimension of treatment—or reform of inefficient drug delivery mechanisms in developing countries, TB treatment will remain inaccessible, ineffective, and ultimately futile. To finally turn the clock back on the spread of TB and its even more dangerous resistant strains, we need a concerted effort spanning industry, state, the public sector, and citizenry...
...show’s elaborate set-design and lighting also have a hand in confusing viewer perception. In the first half of the play, the stage is divided into two raised platforms: one containing a deserted island scene and the other, a fully furnished living room. When the lighting switches between platforms, it seems that there is a scene or temporal switch...
...Harvard women’s sailing team, this weekend brought a do-or-die situation. Finish in the top half of the field at the Reed Trophy, and the Crimson would be guaranteed a spot in the postseason. Finish outside the top seven, and the season would be done...
Vu’s progression towards becoming an artist was in some ways unexpected. Though she says she has always had a passion for art, in her first year and a half at Harvard she focused on Molecular and Chemical Biology, taking only one VES class each semester. Her interest in medicine came from spending time with her father when he was hospitalized with cancer. She was accepted to the Howard Hughes Medical Institute internship program, which she participated in for three years before focusing wholly on her art in her senior year. Though she now has a secondary...