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...These are common genes, we all have them," Michael Owen, a member of the U.K. team, told reporters at a briefing in London announcing the results. "The key issue is what hand of cards you are dealt, the combination of genes you have that determines your risk...

Author: /time Magazine | Title: Breakthrough Discoveries of Alzheimer's Genes | 9/7/2009 | See Source »

...other hand, the discovery of PICALM came as a bit of a surprise. That gene's activity affects the junction between nerve cells, where various neurochemicals work to relay signals from one nerve cell to another. While most of the research attention in Alzheimer's has been on the build up of amyloid protein and tau tangles that strangle nerve function, the identification of PICALM suggests that some part of the disease may have to do with a breakdown in nerve-cell communication at the junctures. "If you had given people a list of genes and said which ones were...

Author: /time Magazine | Title: Breakthrough Discoveries of Alzheimer's Genes | 9/7/2009 | See Source »

Cloud's article misses the point that if you eat the same amount, exercise will make you lose weight. He seems to imply that it is impossible not to eat more. However, the same motivation that keeps you exercising can keep you aware of your diet; these go hand in hand. Jason Anderson, BRUSSELS...

Author: /time Magazine | Title: Of Crunches and Lunches | 9/7/2009 | See Source »

...last three decades, successive Salvadoran governments have tried to curtail the two Maras. In the 1990s the Salvadoran government instituted a policy that became known as the Mano Duro (Strong Hand), that saw thousands of gang members jailed. But Mano Duro has not stopped the gangs. Corruption at the highest levels of government has allowed many leaders to go free or conduct business from behind bars. Saul Turcios Angel, also known as the "Pitbull," ran a kidnapping and extortion ring as part of Mara Salvatrucha. He escaped from a Salvadoran prison last year and was apprehended in Nicaragua earlier this...

Author: /time Magazine | Title: The Gangs of El Salvador: A Growing Industry | 9/6/2009 | See Source »

...mass-produce his cars with controls on the left (one reason, stated in a 1908 catalog: the convenience for passengers exiting directly onto the curb, "especially ... if there is a lady to be considered"). Once these norms were set, many countries eventually adjusted to conform to the right-hand standard, including Canada in the 1920s, Sweden in 1967 and Burma in 1970. The U.K. and former colonies such as Australia and India are among the Western world's few remaining holdouts. Several Asian nations, including Japan, use the left as well - a possible legacy of samurai warriors who wore their...

Author: /time Magazine | Title: Why Don't We All Drive on the Same Side of the Road? | 9/5/2009 | See Source »

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