Word: hdl
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Dates: during 2000-2009
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Millions of Americans already take a drug to lower their LDL, or bad cholesterol, but if things go Pfizer's way, they may end up adding a pill that raises HDL, the good cholesterol that helps keep arteries clean. A study in the current New England Journal of Medicine reports that the drug torcetrapib boosted HDL levels 46%. When it was combined with the LDL-lowering drug Lipitor, the results were even more dramatic: HDL levels rose 61%, and LDL fell even more than it did with Lipitor alone. But will raising HDL levels mean lower rates of heart disease...
...fats found in peanuts and peanut oil) seems to reduce a person's cardiovascular risk even more, according to a new study in the American Journal of Clinical Nutrition. The low-fat diet (in which 18% of calories are from fat) decreased by 12% the dieter's levels of HDL ("good") cholesterol, which protects against heart disease. The moderate-fat diet produced no decrease in heart-friendly HDL. --By David Bjerklie
...reappeared after the first part of the study was completed. By the end of the next six months, the two test groups showed no difference in the amount of weight they had lost. The studies also found that those who ate the low-carb way enjoyed higher levels of HDL, but it's not yet clear whether this boost provides enough of a benefit to the heart to compensate for the extra fat consumed in the Atkins-style diets...
...news reports dubbed it "Drano for the heart," and if the results are confirmed in larger trials, they may signal an exciting new approach in fighting cardiovascular disease, America's leading cause of death. "It" is a genetically rare type of HDL, or "good" cholesterol, dubbed ApoA-1 Milano. First identified 30 years ago in a small group of people living in northern Italy, this super HDL is even more protective against heart disease than regular HDL. In a study released this past fall, researchers injected a synthetic version of ApoA-1 Milano into 47 patients and found that unlike...
...trans-fatty acids. Food manufacturers began using them in place of saturated fats in the 1980s. Trans fats extended the shelf life of certain products, and foodmakers thought they made edibles safer. Turns out trans fats, like saturated fats, raise bad cholesterol (LDL) and may lower good cholesterol (HDL). As if that weren't bad enough, they may also increase the risk of diabetes. Current labeling guidelines don't require manufacturers to state how many grams of trans fats are in a product, but the FDA has called for food labels to come clean. Look for trans-fat grams...