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...only distract from the urgent need to find a cure. "There are so many things that you can't overcome with Alzheimer's - we can't get too excited by these low-tech treatments. They can help patient care but they will never deliver a solution," says Susanne Sorensen, head of research for the Alzheimer's Society U.K. "We need more clinical trials [for vaccines and drugs]. There's no substitute." (Read "The Year in Medicine 2008: From...
...race is necessary because the viruses are very good at setting traps for the vaccines. The immune system is calibrated to crank out antibodies in response to the proteins it sees in the greatest quantities. Over the ages, the flu virus has thus evolved a shape like a bobble-head doll, and it covers the head portion with proteins it can easily change or do without. The vaccine targets these ever changing spots, and by the time the next season comes around, the change has been so great that the vaccine is useless. (Read "How Long Does Flu Immunity Last...
...strategy takes a bead on a much smaller region, closer to the soles of the viral bobble head's feet, where the virus fuses to the cell it infects. These regions mutate less rapidly, and in fact, in the recent study in mice, published in the current issue of Nature Structural & Molecular Biology, they did not mutate at all. "If we use this approach judiciously, we should be able to keep this pocket conserved and not develop drug resistance to it," says Dr. Wayne Marasco of the Dana Farber Cancer Institute, a co-author of the paper. "The exciting part...
...really controlled the tempo of the game,” said Slaughter. “We played with a lot of discipline and I think that made the difference today.”Although the Crimson was able to knock out their first top-10 team in head coach John Tillman’s time in Cambridge, Harvard will not be resting on its laurels. The Crimson has hard work ahead of it as the team attempts to surpass its 6-8, 1-5 conference record from 2008.“I definitely think this win is a great start...
...huge for Princeton, as Harvard tried to charge back and get a lead. Each time Harvard got closer, Maddox had two more free throws to put the Tigers back up by three. With Harris in, it might have been a different story. Without, the team was left scratching its head, thinking what to do next. —Staff writer Walter E. Howell can be reached at wehowell@fas.harvard.edu...