Word: hedgehog
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Next, Riddle said, researchers must demonstrate that Sonic hedgehog is necessary as well as sufficient for limb development...
Apparently, cells sense the concentration of Sonic hedgehog and then decide what type of cells they should be--for example muscle, bone, or skin cells--and thus determine the ultimate shape of the embryo...
...fact, according to Tabin, in research subsequent to the publishing of the paper, his lab has isolated the human Sonic hedgehog gene. He has also mapped the genes responsible for certain genetically-determined diseases in humans to the same place on the chromosome as Sonic hedgehog...
Tabin suggested using the names of different species of hedgehogs. His lab had called the previous three genes isolated from this family Indian hedgehog, moonrat hedgehog and desert hedgehog, for the gene's ability, when mutated, to give fruit flies the bristly appearance of a hedgehog...
...Riddle claimed that he didn't like any of the choices. According to Riddle, a co-author of one of the three papers, he went home and inadvertently picked up a copy of Games magazine, only to see an advertisement for Sonic Hedgehog 2, the SEGA Genesis video game...