Word: helsinki
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...their misfortune result from blind chance, a shared exposure to some cancer-causing trigger in the environment or their diet? Or could they have inherited a rogue gene that made them more susceptible to malignancy? Now a team led by scientists from Johns Hopkins University and the University of Helsinki believe that they have found the answer. "What has heretofore been called familial colon cancer can now be called heritable colon cancer," says Dr. Bert Vogelstein, professor of oncology at Johns Hopkins. "Our groups have proved beyond any shadow of a doubt that a genetically determined predisposition to colon cancer...
What is remarkable -- and entirely novel -- about the gene is that it may actively promote the accumulation of genetic errors, eventually causing a cell to become malignant. That was "a major surprise," says Albert de la Chapelle, chairman of the department of medical genetics at the University of Helsinki. "It doesn't work at all like we and others had thought." As reported in Science, the researchers estimate that 1 in 200 people carries the defective gene. Of the 95% of them who will eventually develop cancer, 60% will get colon cancer and the rest will develop a variety...
Those facts may remain unclear for some time. Epstein is in Helsinki, Finland, until the end of this week...
Indeed, he's something of a square. A self-described "uptight, serialism- oriented, would-be intellectual," Salonen was educated as a composer in his native Helsinki, in the manner of such daunting dodecaphonists as Arnold Schoenberg, Luigi Nono and Elliott Carter. His conducting career began as an adjunct to his composing at the Sibelius Academy, but it took off in 1983 when he stepped in for Michael Tilson Thomas on a week's notice to lead the London Philharmonia in Mahler's woolly mammoth, the Symphony No. 3 -- despite the fact that prior to the call he had never even...
...quiz contestants nervously blurting out wrong answers, some incumbent Presidents have lost debates because of pressure-of-the-moment gaffes. Jerry Ford made his bizarre 1976 declaration that Poland was not a communist country and foolishly stuck to it for five days because he misremembered a briefing on the Helsinki Accords, which implied recognition of Soviet control of Eastern Europe. Did it really make substantive -- as opposed to political -- difference that in 1980 Jimmy Carter blurted out that he had been discussing arms control with his precocious 13-year-old daughter...