Word: hemangioma
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Dates: during 2000-2009
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...research, published Oct. 19 in the journal Nature Medicine, claims to have found the mechanism by which the nonmalignant tumor grows and to have identified how to prevent the abnormal growth that causes infantile hemangioma...
...study conducted by Olsen’s team observed tissue from nine infantile hemangioma patients at Harvard-affiliated Children’s Hospital and compared it to healthy tissue from boys’ foreskins...
According to Olsen, anti-VEGF treatments already approved by the Food and Drug Administration for other conditions, including other cancers, could be used to prevent or limit the development of the infantile hemangioma tumor tissue...
Teaming up with a group from Children’s Hospital, Olsen’s laboratory and the newlyweds set out to understand the mechanism of the infantile hemangioma tumor, and to eventually find a treatment...
Olsen said that he still hopes to conduct clinical trials to confirm the benefits of anti-VEGF therapy in treating infantile hemangioma. But the team is also looking at other possible cures, including a way to induce pre-mature cell death in the endothelial cells. Another option would be to manipulate the mechanism by which the tumors naturally shrink, but that process is not yet understood...
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