Word: hemophilia
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...seen by Massie, the Romanovs' 300 years' rule was doomed by the Czarevich's hemophilia: it put the imperial pair in the oily hands of Rasputin, whose prayers they believed would heal their more than fragile son Alexis. Rasputin not only destroyed the morale of the aristocracy, he also made it impossible for Nicholas to heed sensible advice until it was too late. And he fatally fractured the image of the Czar in the mind of the masses. The imperial pair saw a calumniated saint in Rasputin; the people, in the words of a monarchist member...
...parents carry the abnormal gene, and it is proved by the birth of one child with cystic fibrosis, there is a one-in-four risk that any subsequent child will also be afflicted. Other diseases in the bad-risk group: some forms of mental retardation, deafness, muscular dystrophy and hemophilia-like bleeding disorders. The counselor's advice to parents with one child suffering from these has to be: if you want more children, adopt them...
Often, because of guilt feelings in the mother who cannot suffer from hemophilia but has transmitted it to her son,* a young bleeder is maternally overprotected. The father feels left out and takes little interest in the boy. Even legitimate parental concern for a hemophiliac son's safety can transmit unnecessarily restrictive fears to him. The reaction in either case, says Dr. Agle, can be self-destructive. In an effort to deny his fears, the hemophiliac boy may take what are, for him, absurd risks by jumping from trees, riding motorcycles and even picking fist fights...
...Classical hemophilia, resulting from the absence of a clotting factor from the blood, is carried in an X chromosome. The mother-carrier, with one such abnormal chromosome, derives it from her father. West Germany's Dr. Widukind Lenz, of thalidomide fame, now reports that the risk of a woman's inheriting such a mutation increases sharply with the father's age at the time of her conception...
...normal enough for prospective parents to wonder about the sex of their unborn child. When their doctor shares their curiosity, though, he may well fear the presence of some sex-linked hereditary disease such as hemophilia, or certain disorders accompanied by mental retardation...