Word: hemophiliac
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...known that the spleen is somehow involved in the production of AHF, but just how is not yet clear. Experimenting with pigs, the Boston City Hospital surgeons found that a normal spleen begins to produce more AHF when perfused with the blood of a hemophiliac. To one of the surgeons, Dr. John C. Norman, this suggests the possibility of transplanting a normal spleen into a hemophiliac, so that his abnormal blood might stimulate the new spleen into plentiful production...
...transplanting a heart, liver or even a kidney. But Dr. Norman emphasized that further experimentation-with dogs-must be conducted before spleen transplantation is attempted on a human being. Then, in all probability, a donor's spleen will be enclosed in a plastic bag, hooked up to a hemophiliac's circulating system and hung externally on his arm until it is certain that the method works...
Often, because of guilt feelings in the mother who cannot suffer from hemophilia but has transmitted it to her son,* a young bleeder is maternally overprotected. The father feels left out and takes little interest in the boy. Even legitimate parental concern for a hemophiliac son's safety can transmit unnecessarily restrictive fears to him. The reaction in either case, says Dr. Agle, can be self-destructive. In an effort to deny his fears, the hemophiliac boy may take what are, for him, absurd risks by jumping from trees, riding motorcycles and even picking fist fights...
Until a few weeks ago, being a hemophiliac never had seriously bothered 31-year-old Willie Cooke, a radio repairman in Four Oaks, N.C., despite intermittent hospitalization and transfusions for minor injuries. But when he had a tooth pulled early last month, intensive bleeding (20 to 25 pints a day) set in. At Duke University Hospital in Durham, doctors put him on the critical list, called for blood donors. As Willie grew weaker, an old gastric ulcer opened up, added to the blood loss. Clotting drugs (e.g., thrombin and Gelfoam) and antihemophilic globulin flown in from the Health Department...
...three of the other female hemophiliacs' families were British, all fitted the classic Mendelian inheritance pattern: a father-bleeder, a non-bleeding mother-carrier. One of the hemophiliac daughters successfully bore a child (TIME, July 16, 1951), but was later forced to undergo surgical removal of the uterus after she nearly bled to death...