Word: hench
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...practical value. Meanwhile, Reichstein ran the number of hormones and similar substances found in the adrenal glands to 28, and Kendall kept trying to synthesize compound E, or something like it. At last Kendall and others succeeded, and late in 1948, a colleague at the Mayo Clinic, Dr. Philip Hench, directed the first injections of cortisone to human victims of rheumatoid arthritis. The results were dramatic. Suddenly, a vast new field of medical research was opened...
...Finger Exercises." Long before Hench and Kendall showed the near-miraculous power of ACTH and cortisone to reverse the course of rheumatoid arthritis (TIME, May 2, 1949), Dr. Selye had outlined the theory into which their facts fitted so neatly. He has become the world's outstanding expert on the endocrine glands-though many dispute some aspects of his theories and some question his methods...
...Treatment. Much of the raising of false hope could be laid to the showmanship which marked the first news. Patients who had been crippled were photographed dancing a jig after a few shots of either hormone. But the research team headed by Drs. Philip S. Hench and Edward C. Kendall which touched off the foofaraw ends a solemn, 120-page report in the Archives of Internal Medicine with these sobering words...
This was a far cry from the optimism still being voiced in less-informed quarters. The truth is, when the hormone injections are stopped, the rheumatic miseries usually come back promptly in full force. Drs. Hench and Kendall saw one patient win relief for ten months and another for twelve. But in such an erratic disease as arthritis, the same things might happen without hormones...
...cortisone. A few Swedish, British and U.S. investigators claim wondrous results with desoxycorticosterone acetate ("DOCA," an adrenal hormone) and vitamin C injections given within a few minutes of each other. Others in the U.S. sing the praises of such hormones as 21-acetoxy-pregnenolone. None of these, said Drs. Hench and Kendall, have stood up under proper testing...