Word: heparin
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Dates: during 1930-1939
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...filled with urea, they anesthetized him, connected an artery and vein to a vein and artery of a healthy, anesthetized dog. The small connecting pipes were attached to a specially designed pump which exchanged more than six quarts of blood an hour in each direction. A solution of heparin (a phosphorus compound found in the liver) was introduced into the blood to prevent coagulation. No change was made in the blood volume of either animal, but the two blood streams were thoroughly mixed until the urea of the nephrectomized (kidney-less) dog was distributed fairly evenly throughout the blood...
...since the last heartbeat, sallow young Dr. Robert E. Cornish moved Lazarus II to a seesaw-like device called a teeterboard. There he opened one of the terrier's thigh veins to admit a saline solution saturated with oxygen and containing the heart stimulant adrenalin, the liver extract heparin and some canine blood from which the fibrin (coagulating substance) had been removed. While he breathed gustily into the dog's mouth, his assistant rubbed the kinky-haired little body, rocked it on the teeterboard. The stimulant solution sank in a glass gauge as it seeped into the corpse...