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...Laboratories LLC (SPL), a Waunakee, Wis., company started in 1976 by Oscar Meyer, of hot-dog fame. (The connection: pigs naturally produce proteins used in pharmaceuticals.) CZ-SPL makes a key ingredient, what in the pharmaceutical business is called an active pharmaceutical ingredient, or API, for a drug called heparin, a blood thinner that is widely used by kidney-dialysis and postsurgical patients to prevent blood clots. The team found little unusual and gave the facility a clean bill of health...

Author: /time Magazine | Title: Heparin's Deadly Side Effects | 11/13/2008 | See Source »

...after two months of dialysis using heparin produced by Baxter, Bonnie Hubley was rushed into intensive care. She had developed diarrhea, vomiting and eventually severe pain in her chest and abdomen. She deteriorated rapidly and by Dec. 19 was unconscious and on a breathing tube. Stunned doctors at the Toledo, Ohio, hospital told Leroy there was no hope. "She was gone," he says. So with "Christmas carols playing in the background," he says, "we said our goodbyes, and my wife of 48 years drifted away...

Author: /time Magazine | Title: Heparin's Deadly Side Effects | 11/13/2008 | See Source »

...past, catheters and stents were all made in one standard size--to fit men's larger arteries. As a result, women suffered more complications and a much higher risk of death from angioplasty. Also, until about three years ago doctors prescribed the same doses of the blood thinner heparin for men and women, leading to greater internal bleeding in women. Smaller catheters and stents and lower doses should give women better results...

Author: /time Magazine | Title: The No. 1 Killer Of Women | 4/28/2003 | See Source »

...long air flights (the so-called coach-class syndrome). For patients who are already at high risk of clots--because they've had them before or have other circulatory problems like large varicose veins--something completely different seemed to do the trick: a shot of the blood thinner heparin one or two hours before flying cut the risk of clotting to nearly zero...

Author: /time Magazine | Title: The Heart Beat | 11/26/2001 | See Source »

...folks from the Cryonics Institute (CI) rush to the scene and await the inevitable, as undergoing the freezing process while still alive is illegal. When you are pronounced "dead," the cool-down immediately begins with application of ice to your head and body. At this point the powerful anticoagulent heparin is injected to prevent massive blood clots from making you even deader. Then your clammy corpse is transported to the CI facility in Clinton Township, MI, where your blood is replaced with increasing concentrations of, um, antifreeze. After washing out blood and "perfusing" with "cryoprotectant" the "dead" body is lowered...

Author: By B.j. Greenleaf, | Title: Hooked on Cryonics | 3/6/2001 | See Source »

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