Word: heparin
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...they reached the lungs. That was 20 years ago. Schulte's physician, Dr. Irving Wright, casting around for a drug to prevent clot formation (none had yet been proved effective in man), appealed to Nobel Prizewinner Charles H. Best, co-discoverer of insulin. He wanted some of the heparin that University of Toronto laboratories had just begun to extract from beef lungs and liver. Dr. Best sent all he could spare...
...little more than two weeks, Patient Schulte's condition improved and the clotting appeared checked. Since then he has had infrequent, mild recurrences, has led an active life. From the presidency of Park & Tilford, Arthur Schulte moved to investment banking in Wall Street. Last week, in gratitude for heparin's help, ex-Patient Schulte footed the bills for a Manhattan conference staged by the New York Heart Association on progress in anticoagulant drugs...
Some volunteers go on diet rotation: one week with low fat, one with no fat, one on high fat. During each stage, the human guinea pigs are tapped for blood samples for studies of the fat content. Some get a regular prebreakfast injection of heparin (a drug usually administered to prevent bloodclotting) to see what effect it has on fats in the blood...
...temperature and forbidden to smoke (smoking lowers skin temperature, slows down recovery by hampering circulation in the extremities). The second method follows most of the same rules but adds four injections a day of "frostbite solution"-250 ccs of alcohol, procaine, and, unless the man is wounded, the anticoagulant, heparin, in a 5% solution of glucose and water...
...volume (and hence, blood pressure) at the beginning, so that there would be little or no loss from uncontrollable bleeding at the site of operation. They opened an artery in the wrist and let the heart pump the blood out through a rubber tube into a collecting flask (containing heparin, to prevent clotting). By an ingenious arrangement of valves and flasks, the doctors could draw more blood at will, leave the supply stationary, or pump it back. With the systolic blood pressure down to about 80 mm., the surgeons could operate more confidently because they had the patient...