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...genetic screens included one set of 101 gene changes that have been linked to heart disease as well as to factors that can contribute to heart disease, such as high blood pressure, diabetes and high cholesterol. The second genetic screen was a leaner library of 12 genetic changes for which published studies have found a definitive link to heart disease only...
Anyone who has seen a doctor recently knows the major culprits of heart disease - high cholesterol, high blood pressure, smoking, too little exercise. For years, physicians have been warning their patients about these risk factors for heart attack and stroke. But with the explosion of research on the genetic drivers of disease, a group of experts at Brigham and Women's Hospital in Boston wondered how these tried and true markers of heart problems would stack up against the predictive power of the latest genomic science...
...Framingham score is a decades-old tool established by a landmark study that began in 1948 (and continues today), which identified seven major predictors of heart disease - older age, diabetes, smoking, high blood pressure, high total cholesterol, low HDL cholesterol and a BMI in the overweight or obese range. The Reynolds score is a more recent screen that uses the Framingham risk factors as a base and adds another, inflammation, which in recent studies has been linked to an increased risk of heart disease. (See the 50 best inventions...
...This is something very important going forward,” he said in an interview Thursday. “In the next ten to 20 years, there’s going to be a very, very significant increase in Latino students as a proportion of high school seniors...
Even Iran's irrepressible Twitter-powered opposition could not mask its disappointment. Before the Feb. 11 celebration of the 31st anniversary of the Iranian revolution, some estimates predicted antigovernment turnout to be as high as 2 million. Very little of that materialized. Now Iran's emotionally deflated opposition is collectively scratching its head to explain not only what happened but also what it means for the future of the Green Movement, as the opposition calls itself...