Word: highly
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Dates: during 2010-2019
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...upshot is that the high castle walls built over the past 100 years by the film industry to establish privilege and protect monopolistic profits may soon come tumbling down, just as they have for the music industry. In keeping with the old storyline, the nimble David looks set to vanquish the myopic and overconfident Goliath...
...findings were published online in the New England Journal of Medicine (NEJM). The results of two other related studies were also published online: one large trial also looked at the effect of reducing blood pressure in diabetes patients; another trial, involving 9,300 patients who had high blood sugar and were at high risk of developing diabetes, measured the benefit of drugs that blunt the sharp peaks and valleys in blood glucose levels that occur after eating. Neither study showed benefits of these treatments in reducing risk of heart disease...
...doesn't mean they are the final word on the tested treatments. In the blood-fats arm of the ACCORD study, for instance, about 40% of the volunteers had already had a previous heart event and the remainder had risk factors, other than diabetes, that put them at high risk for heart disease, notes Dr. Om Ganda, director of the lipid clinic at Joslin Diabetes Center in Boston. That means the trial was not truly a primary-prevention study designed to test whether aggressive drug treatment could prevent a first heart attack in newly diagnosed diabetes patients...
...production of cholesterol, and a fibrate, which mops up harmful triglycerides in the blood and boosts levels of "good" cholesterol. But all of the volunteers either already suffered from heart disease, or had two or more major risk factors for heart problems - including cigarette smoking, family history and high cholesterol - in addition to diabetes. That may have pushed their diabetes too far along to allow them to see any benefit from the drugs. "This may be too late a state to expect major benefits from the medications," says Ganda...
Freshman Harry Krieger also had a breakout game as goalkeeper, notching a career-high 13 saves, including 9 in the second half...