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Even acknowledging the lack of data, however, researchers like Dr. Scott Grundy of the University of Texas Southwestern Medical Center in Dallas have long argued that statins should be prescribed to women at moderately high risk for heart disease. Grundy says the underrepresentation of women in drug trials does not discount statins' benefit; it results only in a failure to show a statistically significant effect. Grundy was one of the authors of the 2001 national guidelines for lowering cholesterol and the 2004 revisions that greatly expanded the use of statins - and were criticized because of his and other authors' ties...
...trial, a large, industry-funded study that sought to compare the effectiveness of the statin Crestor (rosuvastatin) with that of a placebo in healthy patients. The study, which ended in 2008, involved nearly 18,000 participants - including 6,801 women, more than in any previous statin trial - who had high levels of C-reactive protein, a risk factor for heart disease, but did not have high cholesterol...
Margaret, 59, who asked that her last name be withheld, says her experience with statin side effects was harrowing. Margaret was in her early 50s and had high cholesterol and diabetes when her doctor put her on statins. Soon after, she says, she forgot how to do basic math and got lost driving to familiar places. But when she described the symptoms, she says, her doctor refused to believe they were related to the drugs. "I felt like I was going crazy," says Margaret, "but within a week or two of stopping the statins, my brain started to work again...
...President correctly refocuses the goal of our nation's public schools from simply giving students a high school diploma to making sure they are ready for college or a career. In other words, he wants to make sure a high school diploma means students actually have the skills they need to compete in an increasingly global workforce. Obama would define school success by how much improvement students make from grade to grade, no matter where they started, as opposed to the current system, in which schools are judged on students' absolute performance, not their progress. Obama's model is similar...
...many people have reached that breaking point with their Federal Government-and are they acting alone or together? If you count just the people who are arming themselves against the day when U.N. tanks roll through the heartland to establish the one-world order, estimates range only as high as 100,000. But if you include all the people in as many as 40 states who respond to the patriot rhetoric about a sinister, out-of-control federal bureaucracy -- all the ranchers fed up with land- and water-use policies, all the loggers who feel besieged by environmentalists...