Word: hiv
(lookup in dictionary)
(lookup stats)
Dates: during 1990-1999
Sort By: most recent first
(reverse)
Gabuzda used this discovery to try to find out if any of these proteins allowed HIV into microglia. She found that CCR5, and another protein--CCR3--are part of the complex that is the brain's gate for HIV...
These molecules had been suspected of being able to channel HIV "but this had only been suggested in recombinant DNA experiments," says Gabuzda. "This is the first time CCR3 has been shown to be the doorway...
...known that people who are deficient in the CCR3 receptor show no known abnormality, and further that they are highly resistant to HIV infection," says Gabuzda...
These facts are raising hopes that a drug which blocks the receptor could inhibit HIV's infection of the brain...
...Theoritically even if HIV were eliminated totally by other drugs from the body, it could resurface from hiding in the brain.' --Dan H. Gabuzda, Associate Professor of Neurology, Dana-Farber Cancer Insititute