Word: hiv
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...HIV protease cuts the virus’ proteins and enzymes into smaller pieces which then go on to infect new cells...
Currently, there are three categories of commercially available drugs being produced to combat HIV infection at various places in the virus’ replication cycle: nucleoside reverse transcriptase inhibitors, non-nucleoside reverse transcriptase inhibitors and protease inhibitors...
Using information from DiRienzo’s study, physicians can now distinguish HIV with genetic coding that is resistant to certain drugs and prescribe alternative medication...
...blocking HIV protease, amprenavir—the focus of DiRienzo’s study—and other drugs keep the virus from making copies that can infect cells. HIV protease inhibitors slow virus production at the end stage of virus replication...
DiRienzo said he worked to uncover the link between mutations in the protease-coding region of HIV, and their ability to resist protease-inhibitor antiretroviral drugs...