Word: hiv
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Reinherz, who is faculty director of the Cancer Vaccine Center at Dana-Farber, said he hoped that such an antibody would be a valuable tool in the fight against HIV...
...researchers examined a region on the surface of HIV that is consistent across many strains of the virus: the membrane proximal ectodomain region (MPER...
...team tested their findings using a particular BNA called 4E10. They found that 4E10 was able to pull portions of MPER out of the viral membrane and attach itself to the virus. The antibody then prevents the viral membrane from fusing with the membranes of human cells, effectively blocking HIV infection...
Barton F. Haynes, director of the Duke Human Vaccine Institute and the Center for HIV-AIDS Vaccine Immunology, said that the authors of this paper present key information about how HIV hides MPER from human antibodies...
According to Haynes, however, some important questions remain unanswered, including how neutralizing antibodies interact with HIV in the body...