Word: hla
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Some of that resilience may be linked to human leukocyte antigen (HLA) genes, a group clustered on chromosome 6 that affects vulnerability to such autoimmune diseases as lupus, rheumatoid arthritis and multiple sclerosis. Centenarians living in Okinawa, for example, have variants of HLA that tend to protect against those diseases. Perls has found a region on chromosome 4 that centenarians and their siblings and children in the U.S. seem to have in common and that sets them apart from shorter-lived individuals. The finding has not yet been replicated by other groups, but Perls expects to publish a paper...
...perplexed and disappointed" with the generals' refusal to grant him a visa for the past six months so that he could try to foster dialogue between the two sides: "I really cannot understand why I'm being denied access." Apparently the change in tactics was effective. Junta spokesman Colonel Hla Min announced last week that the U.N. envoy would be allowed back into Burma for four days beginning June 6. Several analysts said the generals may have relented because of hints the European Union and the U.S. were considering broadening economic sanctions against the regime. Burma's banking system...
...chance that potential donors will actually go on to donate is about 25 to 30 percent, said drive coordinator Adrienne Harrison. That will happen if a student’s HLA type—the type of tissue needed by bone marrow patients—matches that of a patient listed in the registry...
...people of the same ethnicity are the most likely to have matching HLA types after family members, Herrmann said...
Majewski and her husband first volunteered as donors 10 years ago, when a friend asked them to help a family member with leukemia. They underwent initial blood tests, known as HLA typing, for a series of four genetically determined traits that, along with two more traits tested at a second level, must closely match those of the patient for a transplant to be accepted by the body. Neither Teri Majewski nor her husband matched, but they let the American Bone Marrow Donor Registry keep their records...