Word: hler
(lookup in dictionary)
(lookup stats)
Dates: all
Sort By: most recent first
(reverse)
...letter was buried deep in the Aug. 7, 1975, issue of the journal Nature. It described a method of producing huge quantities of very pure, very precise antibodies, the disease-fighting guided missiles of the immune system. The technique, said Authors César Milstein and Georges Köhler of the Medical Research Council Laboratory in Cambridge, England, "could be valuable for medical and industrial use," although Milstein worried about such conjecture being "immodest...
...years later that prediction has proved to be an enormous understatement. Monoclonal antibodies have revolutionized biomedical research and are becoming important weapons in treating and diagnosing disease. It therefore came as no surprise to the scientific community last week when Argentine-born Milstein, 57, and West German Köhler, 38, who is now at the Institute for Immunology in Basel, Switzerland, were given the 1984 Nobel Prize for Medicine. They shared the award with Niels Jerne, 72, founding director of the Basel institute and a pioneer thinker in immunology...
...technique builds on pioneering work with mice done five years ago by César Milstein and Georges Köhler in Britain. By injecting foreign substances into the animals, they stimulated the production of antibodies against the invaders. Then they removed the animals' spleens, a major site for antibody production, and mixed the organ's antibody-producing cells with cancer cells. The result: hybrid cells, dubbed hybridomas, that inherited from the spleen the ability to produce antibodies and from the malignant cells the ability to replicate themselves indefinitely. These hybridomas produce identical copies of themselves-clones...
Great Stud-Farms of the World by Monique and Hans D. Dossenbach, Hans Joachim Köhler (Morrow; 289 pages; $35). The authors have composed an encyclopedic and lushly illustrated celebration of horses and the places where they are bred. Surely the animal has not received such intelligently loving attention since Siegfried Sassoon published his Memoirs of a Fox-Hunting Man in 1928. After tracing the history of horse breeding to the time when the animals first entered the service of man some 5,000 or 6,000 years ago, probably in the steppes north of the Caucasus, the authors...
...note relayed to the West German ambassador's residence in Guatemala City had been scribbled hastily by the ambassador himself. "Do not be afraid," wrote Count Karl von Spreti, 62, to his son Alessandro, 11. "My health is good, my heart is as stout as the Bühler Höhe [a well-known hill in Bavaria's Black Forest]. I am treated with respect and courtesy. I embrace you fondly. Papi." Last week, shortly after he wrote that note, the ambassador was murdered with a bullet behind the right...