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...thing is certain. The news won't help Roche Holding AG, the Swiss holding company for Tamiflu manufacturer Hoffman-La Roche. Tamiflu sales dropped off sharply in the second half of 2007, Roche announced this week. But the main reason wasn't drug-resistance; it was simply a saturated market. As countries meet their targets for an anti-flu-pandemic Tamiflu stockpile, global demand for the drug is tapering off. For now, at least, those national stockpiles still offer an advantage: To date, the H5N1 bird flu shows only limited resistance to the drug...

Author: /time Magazine | Title: Drug-Resistant Flu Virus on the Rise | 1/31/2008 | See Source »

...several medications on the market that limit the body's ability to digest fat, Xenical (also called orlistat) was approved for adults in 1999. In fact, it was the FDA that originally encouraged Xenical's manufacturer, Hoffman-La Roche, to study its effectiveness in the pediatric population. The company selected 357 obese kids ages 12 to 16 and put them on both Xenical and a low-fat diet. As a control, 182 equally overweight teens were put on the same diet and a placebo. At the end of the study, the Xenical children had lower body-mass indexes than...

Author: /time Magazine | Title: Health: Fat Pill For Teens | 12/29/2003 | See Source »

Rohypnol is a sleeping pill in Europe, produced by Switzerland-based Hoffman-La Roche Pharmaceuticals. The company’s latest pills turn blue in alcohol to avoid abuse, but there are American manufacturers that produce imitation drugs, according to Dr. Christopher M. Coley, a general internist...

Author: By David B. Rochelson, CRIMSON STAFF WRITER | Title: Students Treated in Date Rape Drugging | 10/28/2003 | See Source »

...this makes even Hoffman-La Roche, Xenical's manufacturer, nervous. "We're trying to encourage patients to seek proper medical supervision," says president Patrick Zenner. Still, there's nothing they--or the FDA--can do about offshore pill pushers. (Besides, the feds have other online woes; last week they warned users against relatives of the so-called date-rape drug GHB, which are available online under names like Serenity, Enliven and SomatoPro...

Author: /time Magazine | Title: Fat Drug Flies In Cyberspace | 5/24/1999 | See Source »

...were dashed by revelations that they can cause heart valve damage. But a study published Wednesday in the Journal of the American Medical Association says that orlistat has no such life-threatening side effects. Where Redux and Fen-Phen worked in the brain to suppress appetite, orlistat, made by Hoffman-La Roche, blocks the absorption of some fat in the intestines...

Author: /time Magazine | Title: FDA Advisory Board: New Diet Pill Is Safe | 1/20/1999 | See Source »

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