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Word: hopelesses (lookup in dictionary) (lookup stats)
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...encouraged by an effete corps of impudent snobs who characterize themselves as intellectuals." "In the United States today," Agnew told a 1970 audience in San Diego, "we have more than our share of the nattering nabobs of negativism." He went after "pusillanimous pussyfooters" and "vicars of vacillation" and "the hopeless, hysterical hypochondriacs of history...

Author: /time Magazine | Title: NAYSAYER TO THE NATTERING NABOBS | 9/30/1996 | See Source »

...development of drugs for schizophrenia, one of the most perplexing and devastating of all mental illnesses, was an early success story. After several decades as a hopeless research backwater, the schizophrenia field was reborn in 1989, when the U.S. Food and Drug Administration approved a remarkable drug, clozapine (brand name: Clozaril). Made by the Swiss pharmaceutical firm Sandoz, Clozaril was aimed at patients who did not benefit from other drugs. While traditional antipsychotic drugs such as chlorpromazine (Thorazine) and haloperidol (Haldol) work by blocking dopamine receptors, Clozaril appears to bind to serotonin receptors as well. "It is what we call...

Author: /time Magazine | Title: TARGETING THE BRAIN | 9/18/1996 | See Source »

These two words are shorthand for the proposition that the solution to the Clinton mystery is his opponent. Even many Republicans seem to believe that only by nominating a hopeless candidate could they manage to be losing to such a vulnerable incumbent. If Dole in fact loses, the question of how a ruthlessly efficient election machine like the modern Republican party managed to bungle its nomination so badly will be oft pondered. Even if he wins somehow, the question probably won't go away...

Author: /time Magazine | Title: CONVENTION '96: SITTING PRETTY | 9/2/1996 | See Source »

...mystery. Is this the luckiest guy around, or what? Count on that becoming a theme if Clinton wins. He wins the presidency with a minority of the vote, he loses Congress for his party and it ends up helping him, the opposition party accidentally gives its nomination to a hopeless candidate: these are just the latest lucky breaks for a politician who fortuitously, as a teenager, had his picture taken with President John Kennedy. No wonder he still believes in a place called Hope...

Author: /time Magazine | Title: CONVENTION '96: SITTING PRETTY | 9/2/1996 | See Source »

Then came the lawyers' turn to examine the bunch of us. The prosecutor was up first and he was hopeless: he stammered, shifted his weight, smiled awkwardly and generally seemed to be a sincere man who, try as he might, could not feign sincerity. We took pity on him and gave him easygoing, helpful answers to his fairly predictable questions ("Do you all understand what 'presumption of innocence' means?" and so on). It was actually fortunate that we got our fill of "generic" courtroom questions from him because we would get no such things from the defense attorney...

Author: By Eric M. Nelson, | Title: In the Service Of Justice | 7/30/1996 | See Source »

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