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...Despite the carping, don't expect a slimmed-down preseason - and the reason is simple, money. "Spring training is lucrative for clubs, lucrative for the cities that host them, and will continue to be popular," says Maury Brown, editor of bizofbaseball.com, a site that tracks the economics of the game. According to a recent study commissioned by the Cactus League, which hosts 12 teams in Arizona, spring training will add $200 million to the state's economy...
...Pfizer's maraviroc, one of the two new compounds described this week, steps in just after HIV has successfully bound to a healthy cell; called an entry inhibitor, it blocks the virus from entering the cell and integrating its viral genetic material into the host cell's genome. In a study of more than 1000 patients who had developed resistance to at least three of the four ARV classes, twice the number of patients given maraviroc versus those taking placebo enjoyed undetectable levels of virus after eight months. The results were enough to convince Pfizer to apply for approval...
...second drug, an integrase inhibitor from Merck, aims to tackle HIV where it hurts the most - by blocking the integrase enzyme, which the virus uses to insert its genes into a host cell's genome and hijack the machinery to churn out more copies of itself. Called isentress, the experimental agent helped 75% of patients reduce their viral load of HIV to acceptable levels, compared with only 40% of patients given placebo...
Poor Wikipedia. Professional Golfer Fuzzy Zoeller is suing one of its contributors for a defamatory cyber-attack. And last year, television host and comedian Stephen Colbert urged his audience to vandalize a Wikipedia entry about elephants to prove the point that in a model where any user can edit encyclopedia entries, those entries are only as good as their source. Take the case of retired journalist John Seigenthaler, a former assistant to Attorney General Robert Kennedy, who was wrongfully accused of involvement in the assassination of Robert and John Kennedy by an anonymous Wikipedia contributor in 2005. Given the controversy...
...good old days. In front of the Barker Center Café, an unobtrusive sign advertises: “Free Coffee. New Hours at the Barker Center. Monday – Friday 9-10 AM.” These new hours are a cutback: the Center used to host twice-daily coffee frenzies from 9-10 a.m. and 3-4 p.m. Dean for the Humanities Diana Sorensen sponsors and provides the free coffee at the Barker Center. “The cost became astronomical,” Dean Sorensen explained in an e-mail. “I know more faculty...