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...separate area of research, Xie at Massachusetts General tested another anesthetic, isoflurane, on a culture of human brain cells. (Isoflurane had already been shown to cause cognitive impairment in rats.) He saw a vicious cycle of apoptosis and the accumulation of beta-amyloid protein - the sticky plaques that build up in Alzheimer's patients' brains - among the cells. But in this case, it may have been an excess of calcium that led to cell death. Xie and his colleagues have since found that the Alzheimer's drug memantine, which works by reducing calcium levels inside cells, can slow the rate...

Author: /time Magazine | Title: Anesthesia: Could Early Use Affect the Brain Later? | 11/3/2009 | See Source »

...only research to associate surgical anesthesia in infancy to cognitive impairment later in life was Wilder's study earlier this year, but the literature on the whole in this area remains inconclusive. So far, the bulk of the evidence comes from studies in lab animals, rather than the human population. "The animal data is convincing," says Wilder. "But we need further studies to see if it's true in humans...

Author: /time Magazine | Title: Anesthesia: Could Early Use Affect the Brain Later? | 11/3/2009 | See Source »

...Some researchers, including Lisa Wise-Faberowski, an assistant professor of anesthesiology and pediatric cardiology at the University of Colorado, Denver, think the effect in humans won't be easy to show. At the ASA conference, Wise-Faberowski devoted her presentation to chiding researchers for worrying prematurely about "anesthesia-induced neurotoxicity," pointing out that it has been seen only in "cell cultures and lab animals." If anesthetics have always been neurotoxic, one slide in her presentation asked, "Why is it only an issue now?" She and others point out that non-human testing of anesthetic safety has an unreliable history...

Author: /time Magazine | Title: Anesthesia: Could Early Use Affect the Brain Later? | 11/3/2009 | See Source »

Without declaring war, True Love Revolution draws a conclusion. Culture reduces us to the sexual, but being human promises so much more. The sexualization of people and relationships hinders our development as human beings. When we embrace the sexual culture that stretches its logic to render us servile, we find ourselves unfulfilled. Abstinence resists cultural messages about human worth. Unlike casual sex, abstinence is empowering because, instead of making sex and uncontrolled lust an end, it makes people...

Author: By Rachel L. Wagley | Title: Something More | 11/3/2009 | See Source »

...These posters are hateful and shameful," says Hafid Ouardiri, a spokesman for Geneva's Islamic Cultural Center and its mosque. "How can this happen in Switzerland, the cradle of human rights?" (See pictures of the Swiss-invented Red Cross...

Author: /time Magazine | Title: Will Switzerland Vote to Ban Minarets on Mosques? | 11/3/2009 | See Source »

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