Word: hwang
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Dates: during 2000-2009
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...there's any consolation for Dr. Woo Suk Hwang, the South Korean stem cell pioneer who abruptly resigned Thursday from an international stem cell facility he helped to found amidst an ethics controversy, it's this: at least his own lab now has plenty of women willing to donate their eggs for research...
...field of mammalian cloning. Since Dolly the sheep was cloned in 1996, scientists have followed with pigs, cattle, mice, rabbits, horses and cats. But though they tried mightily, nobody had ever created a genetic double of man's best friend. Not, that is, until South Korean researcher Woo Suk Hwang and his team at Seoul National University brought Snuppy the puppy into the world--an animal whose entire genome came from a single cell from the ear of a three-year-old Afghan hound. Snuppy's arrival, announced in Nature last week, earned grudging admiration from rival cloners...
...surrogate bitch. Cows, goats and sheep can be thrown into estrus--readiness for pregnancy--by giving them a hormone shot. Not dogs. "You have to monitor hundreds, if not thousands, of dogs every day to figure out when they come into heat," says Westhusin. That's why Hwang's team--which stays on the job seven days a week for 18 to 20 hours a day--was well matched for the task. "We had to be ready to collect oocytes at any time of day, even midnight or early morning," says Hwang, adding, in a masterpiece of understatement. "Our work...
...help pet owners. Cloning Snuppy (the name comes from "Seoul National University puppy") took nearly three years and cost millions of dollars. Hwang's ultimate motive, he says, is to create a research model for making stem cells that could cure disease in people. "Compared with rodents," he says, dog cells "are more similar to human stem cells." GS&C still wants to capture the Fido-cloning market, though, and company scientists are trying to reduce the inefficiencies. Even if they manage to clone a dog, says Ben Carlson, a company spokesman, it won't be cheap. "We're charging...
...next, GS&C has stored the DNA of several rare or endangered animals in its cryogenic freezers, including two types of antelope. But, as the world was reminded last week, the biggest breakthroughs in cloning are now coming from Asia--not just South Korea but also China and Singapore. Hwang won't say what he's planning, but the next logical step would be to clone a primate. Human cloning may still be anathema, but the world seems to be inching ever closer. --Reported by Cathy Booth Thomas/Dallas and Alice Park/New York