Word: hybridoma
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...events saved the field. The first, in 1976, was the discovery of hybridoma technology. This allowed scientists to build exquisitely precise probes to explore cell surfaces and search for CAMs. The second boost came in the mid-1980s, when M.I.T.'s Hynes noticed a resemblance between research coming from obscure labs working on cancer, immunology, developmental biology and hematology. Hynes began to see that these researchers were all exploring aspects of cell adhesion. In 1987 he drew together these separate lines of research and published a landmark paper in the journal Cell that finally connected the dots...
Davie got in touch with Mallinckrodt Inc., a St. Louis medical supply company also engaged in hybridoma research. The result: a $3.8 million three-year agreement in which Washington University gets funding for research and Mallinckrodt gets copies of all resulting scientific papers-before their publication. If any discoveries are commercially viable, the university will hold the patent and receive royalties; Mallinckrodt will have an exclusive license to market the product. Says Mallinckrodt President Raymond Bentele: "The agreement allows the university to do what it does best-that is, basic research&3151;and it allows us to do what...
...things as the Xerox, the transistor, the laser and the microchip. A lot of Yankeeingenuity is spent, to be sure, on diverting gadgetry, such as a projected palm-size phone and a vacuum cleaner with a memory (a seemingly gratuitous burden). But recent developments in medicine, such as the hybridoma cells for cancer treatment and the creation of insulin through genetic engineering, are making the 1980s look boldly promising...
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