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Psychiatrists have long suspected that there is a physiological basis for severe depression. They know that thyrotropin-releasing hormone (TRH), a substance released by the hypothalamus at the base of the brain, triggers the production of thyroid-stimulating hormone (TSH); now, they hypothesize that it may have another function as well. Drs. Arthur Prange Jr. and Ian Wilson of the University of North Carolina School of Medicine and the North Carolina department of mental health have found that TRH, which can be synthesized in the laboratory, seems to function as an antidepressant. They have used it experimentally to provide apparently...

Author: /time Magazine | Title: Medicine: Up from Depression | 10/30/1972 | See Source »

...seizures in more than three years, four have had only mild attacks, and one has apparently not improved; it is too early to assess the results in the other seven cases. Dr. Keiji Sano, head of neurosurgery at Tokyo University School of Medicine, uses a similar procedure on the hypothalamus. All of his patients were children with serious brain damage and uncontrollably violent behavior; out of 56, all but a few became relatively calm...

Author: /time Magazine | Title: Medicine: Psychosurgery Returns | 4/3/1972 | See Source »

Once he invented something other people actually used. It was part of a complex brain-surgery device for scientists at Berkeley, which enabled an electronic needle to enter a chicken's brain and reach its hypothalamus with out killing the chicken. "It worked so well I had chickens laying double eggs, eating their heads off, or not eating at all. They could have created monster chickens with my instrument," Karl says proudly...

Author: /time Magazine | Title: Nation: The Lonely Passion of Karl E. Smith | 7/20/1970 | See Source »

...Mayer said the affected area of the brain was the hypothalamus, which regulates food and water intake. Dr. Mayer, responding to a question, said. "I would take the damn stuff out of baby food...

Author: NO WRITER ATTRIBUTED | Title: Baby Food Manufacturers Will Suspend Use of MSG | 10/27/1969 | See Source »

...same opinion was expressed independently by Dr. John W. Olney, assistant professor of Psychiatry at the Washington University School of Medicine. Dr. Olney gave infant mice and a rhesus monkey a highly concentrated dosage of MSG and found cell damage in the hypothalamus...

Author: NO WRITER ATTRIBUTED | Title: Baby Food Manufacturers Will Suspend Use of MSG | 10/27/1969 | See Source »

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