Word: iiis
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Dates: during 2000-2009
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...everyone is convinced by that logic. Dr. Robert Schwartz, an editor at the New England Journal of Medicine, says, "Using patients as their own control is a bit shaky, especially for follicular lymphoma." A Phase III randomized trial, more difficult but still possible to conduct even with customized vaccines remains, he says, "the gold standard for proof of efficacy." Dr. Kwak, who is conducting his own Phase III trial of a vaccine for the American pharmaceutical company Biovest, believes his former trainee's results support the case for a therapeutic lymphoma vaccine, but is skeptical about his methods. "Dr. Bendandi...
...customized treatments: it's expensive (an estimated $34,000 per patient), it's difficult to make, and not all pharmaceutical companies (which make profits by mass-producing drugs) are able - or willing - to take on the work of producing a different vaccine for every patient. But with three Phase III clinical trials for idiotype vaccines under way in the U.S., and several other types of custom treatments in development (on March 29, an fda advisory committee found "substantial evidence" that a prostate cancer vaccine is effective, increasing the likelihood of its approval), hopes for cancer vaccines are running high...
Harvard grabbed an early 3-1 advantage, but did not score again until the fourth quarter. The Sagehens, Division III national champions in 2005, chipped away at the Crimson’s lead, tying the game at 3 in the final quarter before surging ahead...
That's why horror films don't need stars. One letter sells the movie: R (meaning kids are restricted from seeing it unless accompanied by an adult). Another lure is the MPAA description of offensive elements, like this one for Saw III: "strong grisly violence and gore, sequences of terror and torture, nudity and language." Parents read this as a warning, kids as a come-on. "'Terror and torture'? I'm there!" Can't see it? Must...
...portraits on display offer an intimate look at Piero's skill. The facing profiles of the Duke and Duchess of Urbino are iconic Renaissance images, especially the Duke, Federico III, one of the Renaissance's most accomplished condottieri, or mercenary barons. Painting with brilliant color and unfiltered realism, Piero doesn't blink at the prominence of Federico's nose and chin, but he never crosses into caricature. His approach gives Piero's portraiture a strikingly modern aspect. "It is almost hyper-realism," Bertelli says. "The faces are gigantic compared to the background landscape, making them monumental." The same attention...