Word: ils
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Dates: during 1980-1989
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Director: Yeah, we're decided all right. I'll take care of everything. Tell the Big Man not to worry, sans detail s'il vous plait. (Turning to the Bag Lady) Excuse me miss, where do you get your political opinions...
...technique was tested on ten different types of cancer in 25 patients, for whom standard treatments had failed. Crucial to the experiment was a potent natural substance called interleukin-2 (IL-2), one of a variety of chemical messengers called lymphokines that help control the activities of the immune system. Studies have shown that IL-2 is capable of transforming certain white blood cells into powerful, anticancer killer cells. Using an elaborate blood-separating apparatus, Rosenberg and his team withdrew white cells from each patient and treated them with IL-2. After incubating for three or four days, the activated...
...report met with a mixture of optimism and caution in the medical community. "A 50% tumor regression is very good," observed Dr. Kurt Stenzel of the Rogosin Institute at New York Hospital, who is also working with IL-2. "But you still want more," he said. "You want it to go away and never come back." Doctors, including Rosenberg, expressed concern about the treatment's side effects. For most of the patients in the NCI experiment, the treatment caused serious fluid retention, with up to 20 lbs. of water accumulating in the lungs, liver, kidneys and elsewhere in the body...
...IL-2 is just one of a number of lymphokines and related natural substances showing promise in the immunological treatment of cancer. Interferons, tumor necrosis factor, interleukin-1 and a substance called colony-stimulating factor all play a role in the normal functioning of the immune system and may ultimately find a place in the treatment of cancer. It has been only within the past five years that genetic-engineering technology has made large quantities of these substances available to researchers. Many physicians believe that IL-2, which has also been genetically engineered, will eventually be used together with some...
Last week the NCI cancer hot lines were besieged with thousands of calls from Americans seeking information about IL-2 treatment. "In many cases, these were people who had no other hope," said Judith Stein of the Cancer Information Service. At present, however, the Institute can treat only eight patients a month and is not accepting new patients. Plans are under way to begin testing the new procedure next year at cancer centers around the country. Dr. Frank Rauscher, a former NCI chief who is now a top official at the American Cancer Society, explained that the excitement in medical...