Word: indinavir
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Dates: during 2000-2009
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...Eisenberg stressed the need for traditional medical doctors to be willing to talk with patients about the herbal or botanical substances they are taking. He cited, for example, evidence that the popular herbal supplement St. John's Wort seriously impaired the ability of Indinavir, an anti-viral drug used to treat AIDS, to function in the blood stream...
WORT-LESS Here's a downer about the wildly popular herbal antidepressant Saint-John's-wort. However potent its many fans may believe the pretty yellow flower's extract to be, it interacts dangerously with two medications: the antirejection drug cyclosporine, used in organ transplants, and the protease inhibitor indinavir, used to treat AIDS. In both cases, Saint-John's-wort reduced blood concentrations of the drug, rendering it less effective...