Word: inhibit
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Dates: during 1990-1999
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...significance of Folkman's finding lies in the protein's ability to inhibit angiogenesis (blood vessel growth), said Noel Bouck, a professor of microbiology and immunology at Northwestern University Medical School. "In order to grow, tumors must produce new blood vessels," she said...
...discovery represents a whole new way to inhibit cancer growth," O'Reilly said. But he warns that researchers are still years away from clinical use. "By all means we have not cured cancer," he said...
...AIDS and tuberculosis, the body makes itself sicker. The second process stymied by thalidomide is the creation of new blood vessels, which is crucial to the development of arms and legs in the fetus. The eventual goal of researchers is to alter thalidomide somehow so that it continues to inhibit TNF without harming nascent arteries and veins...
...that research team, Calvin Harley, has taken a leave from McMaster University to work at Geron Corp. in Menlo Park, California. The company is trying to craft a drug that will block the action of telomerase. "The cancer cell," explains Harley, "is already very old. If we can inhibit telomerase, we might cause the tumor to die after a few doublings." Even better, the fact that cancer cells produce telomerase and that normal cells (save for sperm) don't, says Harley, "gives us hope that we may be able to develop a drug without serious side effects...
During the '80s, several drugs were shown to inhibit the action of leukotriene. All these drugs, however, produced adverse side effects in humans. It wasn't until this year that a drug was found which reduced biological activity without toxic side effects...