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Also close to reality are the so-called antiangiogenic factors, relatively nontoxic compounds that inhibit the growth of new capillaries. The idea behind this new class of drugs is that tumors cannot grow bigger than a few hundred thousand cells--about the size of a peppercorn--without growing their own blood-supply system. Researchers and patients, not to mention the owners of stock in half a dozen biotech companies, are eagerly awaiting results of clinical trials of antiangiogenic factors, which might be used in combination with chemotherapy to knock down big tumors and then prevent any surviving tumors from growing...

Author: /time Magazine | Title: When Will We Cure Cancer? | 11/8/1999 | See Source »

...researchers speculate that these proteins may also inhibit cancer growth...

Author: By Sasha A. Haines-stiles, CRIMSON STAFF WRITER | Title: Folkman Finds Anti-Cancer Substance | 9/22/1999 | See Source »

Researchers at Boston Children's Hospital have discovered a naturally occurring protein fragment which has been shown to inhibit tumor growth in mice, the third isolated at the hospital's labs...

Author: By Sasha A. Haines-stiles, CRIMSON STAFF WRITER | Title: Folkman Finds Anti-Cancer Substance | 9/22/1999 | See Source »

...implanting human tumors into mice and comparing tumor growth, scientists can try to identify which types of human tumors could possibly be used in future to inhibit cancers, according to the Science article...

Author: By Sasha A. Haines-stiles, CRIMSON STAFF WRITER | Title: Folkman Finds Anti-Cancer Substance | 9/22/1999 | See Source »

...challenged by what the next questions are trying to establish why inhibiting angiogenesis [growth of blood vessels] in tha wall will inhibit the disease process," Moulton said. "[The drug] may not just be choking off the blood supply...

Author: By Melissa K. Crocker, CRIMSON STAFF WRITER | Title: Harvard Researchers Discover Heart Drug Prevents Blood Vessel Buildup | 4/8/1999 | See Source »

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